Description

2-Acetamido-4-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of the acetamido and fluorine functional groups, which are instrumental in modulating the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED devices.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing novel fluorination methodologies.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for specialized, high-value chemical products.

Basic Information

Product Name	2-Acetamido-4-Fluorobenzoic Acid
CAS No.	394-27-4
Molecular Formula	C9H8FNO3
Molecular Weight	197.16 g/mol
Synonyms	4-Fluoro-2-acetamidobenzoic Acid; N-(4-Fluoro-2-carboxyphenyl)acetamide; 2-Acetylamino-4-fluorobenzoic Acid; 4-Fluoroanthranilic Acid N-Acetate; Acetamide, N-(4-fluoro-2-carboxyphenyl)-; 2-Acetamido-4-fluorobenzoic Acid; 394-27-4; 2-Acetamido-4-fluorobenzoic acid
EINECS	206-900-5

Quality Control

Our 2-Acetamido-4-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.