Description

5-Fluoro-2-Nitrobenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, which enable efficient introduction of both the fluoro and nitro-substituted benzoyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic scaffold.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Intermediate in the production of complex, high-performance dyes and organic pigments.
• Polymer Modification: Employed to introduce functional side chains into polymers, altering their physical and chemical properties for advanced material science applications.
• Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	5-Fluoro-2-Nitrobenzoyl Chloride
CAS No.	394-02-5
Molecular Formula	C7H3ClFNO3
Molecular Weight	203.56 g/mol
Synonyms	2-Nitro-5-fluorobenzoyl chloride; 5-Fluoro-2-nitrobenzoic acid chloride; 5-Fluor-2-nitro-benzoylchlorid; 394-02-5; NSC 403697; Benzoic acid, 5-fluoro-2-nitro-, chloride
EINECS	206-889-6

Quality Control

Every batch of 5-Fluoro-2-Nitrobenzoyl Chloride is produced and tested under a strict quality management system. We ensure high chemical purity and consistency to meet the exacting standards of synthesis and research. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water. Due to its acid chloride nature and sensitivity to moisture, containers must be kept sealed under an inert atmosphere after opening.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.