Description

2-Nitro-5-Fluorobenzoic Acid, Methyl Ester is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and complex agrochemicals, where its unique nitro and fluoro substituents enable precise molecular modifications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the nitro-fluorobenzene structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and other transformations to introduce functionalized benzoate groups.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2-Nitro-5-Fluorobenzoic Acid, Methyl Ester
CAS No.	393-85-1
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	Methyl 2-Nitro-5-fluorobenzoate; 5-Fluoro-2-nitrobenzoic Acid Methyl Ester; Benzoic acid, 2-nitro-5-fluoro-, methyl ester; 2-Nitro-5-fluorobenzoic acid methyl ester; Methyl 5-fluoro-2-nitrobenzoate
EINECS	206-897-4

Quality Control

Our 2-Nitro-5-Fluorobenzoic Acid, Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our quality protocols are designed to meet the stringent requirements of pharmaceutical and R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.