Description

Methyl 2-Iodo-3-Fluorobenzoate is a high-purity fluorinated and iodinated aromatic ester, serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both halogen substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring halogenated aromatic cores for bioactivity or as synthetic handles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine and iodine atoms enhance stability and biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings, leveraging the iodine atom for selective bond formation.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Fluorine Chemistry: Integral to the study and production of organofluorine compounds, a rapidly growing field in medicinal and materials chemistry.

Basic Information

Product Name	Methyl 2-Iodo-3-Fluorobenzoate
CAS No.	393-78-2
Molecular Formula	C8H6FIO2
Molecular Weight	280.04 g/mol
Synonyms	2-Iodo-3-fluorobenzoic acid methyl ester; Methyl 2-iodo-3-fluorobenzoate; Benzoic acid, 2-iodo-3-fluoro-, methyl ester; 3-Fluoro-2-iodobenzoic acid methyl ester; Methyl 3-fluoro-2-iodobenzoate; 393-78-2; Methyl o-iodo-m-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Iodo-3-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Assay	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.