Description

Methyl 4-Fluoro-2-Hydroxybenzoate is a versatile fluorinated aromatic ester that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and a fluorine substituent, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential anti-inflammatory and antimicrobial agents.
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Used in the research and production of fluorinated components for electronic display materials.
• Organic Synthesis & Research: A versatile reagent for introducing the 4-fluoro-2-hydroxybenzoate moiety into more complex molecular architectures in academic and industrial R&D.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, dyes, and functional materials.

Basic Information

Product Name	Methyl 4-Fluoro-2-Hydroxybenzoate
CAS No.	392-04-1
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	4-Fluoro-2-hydroxybenzoic acid methyl ester; Methyl 4-fluoro-2-hydroxybenzoate; Methyl 4-fluorosalicylate; 2-Hydroxy-4-fluorobenzoic acid methyl ester; 4-Fluorosalicylic acid methyl ester; Methyl 4-fluorosalicylate; 4-Fluoro-2-methoxycarbonylphenol; Benzoic acid, 4-fluoro-2-hydroxy-, methyl ester
EINECS	206-874-5

Quality Control

Our Methyl 4-Fluoro-2-Hydroxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	72 - 76 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.