Description

3-(p-Fluorophenyl)-3-(p-Tolyl)Propionic Acid is a high-purity fluorinated aromatic propionic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorophenyl and tolyl groups, makes it an essential intermediate for creating compounds with tailored biological and physical properties. This product is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in anti-inflammatory and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving performance characteristics.
• Polymer Modification: Incorporated as a monomer or additive to impart specific properties like chemical resistance or altered refractive index in specialty polymers.
• Chemical Research: A versatile reagent in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fluorine Chemistry: A valuable substrate for further fluorination or functionalization reactions in organofluorine chemistry.

Basic Information

Product Name	3-(p-Fluorophenyl)-3-(p-Tolyl)Propionic Acid
CAS No.	390-43-2
Molecular Formula	C16H15FO2
Molecular Weight	258.29 g/mol
Synonyms	3-(4-Fluorophenyl)-3-(4-methylphenyl)propanoic acid; 3-(p-Fluorophenyl)-3-(p-methylphenyl)propionic acid; 4-Fluoro-α,4'-dimethyl[1,1'-biphenyl]-3-propanoic acid; 3-(4-Fluorophenyl)-3-(4-tolyl)propionic acid; p-Fluoro-p'-methylbenzhydrylacetic acid, β-(4-Fluorophenyl)-β-(4-methylphenyl)propionic acid; NSC 403697; 390-43-2
EINECS	Contact for details

Quality Control

Our 3-(p-Fluorophenyl)-3-(p-Tolyl)Propionic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.