Description

2-Fluoro-5-Methoxybenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of fluorine and methoxy substituents, which are essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile reagent for introducing the 2-fluoro-5-methoxyphenyl moiety into more complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	2-Fluoro-5-Methoxybenzoic Acid
CAS No.	367-83-9
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	5-Methoxy-2-fluorobenzoic Acid; 2-Fluoro-5-methoxybenzoic acid; 2-Fluoro-5-anisic Acid; 2-Fluoro-5-methoxy-benzoic acid; Benzoic acid, 2-fluoro-5-methoxy-; 5-Methoxy-2-fluorobenzoic acid; 2-Fluoro-5-methoxybenzoic acid (367-83-9)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.