Description

3-Fluoro-4-Hydroxybenzoic Acid is a fluorinated derivative of 4-hydroxybenzoic acid, serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and a carboxylic acid group ortho to a fluorine atom, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drugs where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the fluorine substituent to improve efficacy and environmental profile.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifying agent in the production of specialty polymers and liquid crystal materials for electronic displays.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., esterification, amidation) to introduce the benzoic acid scaffold with fluorine and phenol functionalities into larger molecular architectures.
• Biochemical Research: Utilized as a probe or substrate in enzymatic studies and for the development of biochemical assays.
• Material Science: Acts as a starting material for creating metal-organic frameworks (MOFs) and other advanced functional materials.

Basic Information

Product Name	3-Fluoro-4-Hydroxybenzoic Acid
CAS No.	350-29-8
Molecular Formula	C7H5FO3
Molecular Weight	156.11 g/mol
Synonyms	4-Hydroxy-3-fluorobenzoic Acid; 3-Fluoro-4-hydroxybenzoic acid; Benzoic acid, 3-fluoro-4-hydroxy-; 3-Fluoro-4-hydroxy-benzoic acid; 3-Fluoro-4-hydroxybenzoic acid (350-29-8); 3-Fluoro-4-hydroxybenzoic acid, 98%; 3-Fluoro-4-hydroxybenzoic acid, 97%
EINECS	206-500-7

Quality Control

Our 3-Fluoro-4-Hydroxybenzoic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and loss on drying for moisture content, to ensure it meets the high standards required for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Melting Point	215°C - 220°C
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.