Description

4-(4-Fluoro-3-Methylphenyl)-4-Oxobutyric Acid is a high-purity organic acid derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorinated aromatic ring and a reactive oxobutyric acid moiety, making it an essential precursor for creating complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Material Precursor: Serves as a starting material for synthesizing fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Material Research: Employed in the development of novel organic semiconductors and charge-transport materials due to its electron-withdrawing properties.
• Custom Chemical Synthesis: Utilized by contract research organizations (CROs) and CDMOs for bespoke synthesis projects requiring fluorinated aromatic intermediates.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including cross-coupling and condensation reactions.

Basic Information

Product Name	4-(4-Fluoro-3-Methylphenyl)-4-Oxobutyric Acid
CAS No.	349-22-4
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	4-(4-Fluoro-3-methylphenyl)-4-oxobutanoic acid; 4-Oxo-4-(4-fluoro-3-methylphenyl)butyric acid; γ-Oxo-4-fluoro-m-toluicbutyric acid; 4-Fluoro-3-methylbenzoylpropionic acid; 4'-Fluoro-3'-methylphenacylacetic acid; 4-(4-Fluoro-3-methylbenzoyl)propanoic acid; 349-22-4; Butanoic acid, 4-(4-fluoro-3-methylphenyl)-4-oxo-
EINECS	Contact for details

Quality Control

Our 4-(4-Fluoro-3-Methylphenyl)-4-Oxobutyric Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.