Description

3-(Trifluoromethyl)Mandelic Acid is a high-value fluorinated aromatic compound, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its trifluoromethyl group imparts unique electronic and steric properties, making it essential for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances efficacy and environmental stability.
• Ligand and Catalyst Development: Used in asymmetric synthesis for creating chiral ligands and organocatalysts critical for enantioselective reactions.
• Material Science Research: Intermediate in the production of specialty polymers and liquid crystals with tailored optical and electronic properties.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes and inhibitors used in biochemical and pharmacological research.

Basic Information

Product Name	3-(Trifluoromethyl)Mandelic Acid
CAS No.	349-10-0
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	α-Hydroxy-3-(trifluoromethyl)benzeneacetic Acid; 2-Hydroxy-2-[3-(trifluoromethyl)phenyl]acetic Acid; 3-(Trifluoromethyl)phenylglycolic Acid; (±)-3-(Trifluoromethyl)mandelic Acid; DL-3-(Trifluoromethyl)mandelic Acid; 3-TFMandelic Acid; 3-CF3-Mandelic Acid; 3-Trifluoromethylmandelic Acid
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Mandelic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.