Description

3-Fluoro-2-Hydroxybenzoic Acid is a versatile fluorinated aromatic building block that combines a carboxylic acid group with a phenolic hydroxyl group, offering unique reactivity for advanced synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom can significantly alter biological activity and metabolic stability. It is primarily utilized in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including potential anti-inflammatory and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine moiety enhances efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in metal-organic frameworks (MOFs) and transition metal catalysis.
• Material Science: Employed in the synthesis of specialty polymers and liquid crystals, contributing to unique thermal and optical properties.
• Chemical Research: A valuable reagent in organic synthesis for introducing the 2-hydroxy-3-fluorobenzoate moiety into complex molecules.
• Fluorescent Probe Synthesis: Used as a starting material for creating fluorophore derivatives used in bioimaging and diagnostics.

Basic Information

Product Name	3-Fluoro-2-Hydroxybenzoic Acid
CAS No.	341-27-5
Molecular Formula	C7H5FO3
Molecular Weight	156.11 g/mol
Synonyms	2-Hydroxy-3-fluorobenzoic Acid; 3-Fluoro-2-hydroxybenzoic acid; 3-Fluorosalicyllic Acid; 3-Fluorosalicylic Acid; 3-Fluoro-2-hydroxy-benzoic acid; 3-Fluorosalicylic Acid; 2-Hydroxy-3-fluorobenzoic acid; Benzoic acid, 2-hydroxy-3-fluoro-
EINECS	206-433-3

Quality Control

Our 3-Fluoro-2-Hydroxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.