Description

[2-(Trifluoromethyl)Phenyl]Glycolic Acid is a high-value fluorinated aromatic building block, essential for synthesizing advanced molecules with tailored properties. Its unique structure, featuring both a carboxylic acid and a trifluoromethylphenyl group, makes it a critical intermediate for creating compounds with enhanced metabolic stability and lipophilicity. This product is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for novel polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	[2-(Trifluoromethyl)Phenyl]Glycolic Acid
CAS No.	339-93-5
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	2-(Trifluoromethyl)mandelic acid; α-Hydroxy-2-(trifluoromethyl)phenylacetic acid; (2-Trifluoromethylphenyl)hydroxyacetic acid; 2-(Trifluoromethyl)benzene glycolic acid; o-(Trifluoromethyl)mandelic acid; NSC 403697; 2-(Trifluoromethyl)benzyl alcohol-α-carboxylic acid
EINECS	Contact for details

Quality Control

Our [2-(Trifluoromethyl)Phenyl]Glycolic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.