Description

Methyl 3,5-Difluoro-4-Methoxybenzoate is a high-purity fluorinated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its precise molecular structure, which enables the efficient construction of complex molecules for demanding applications. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluoromethoxy or related aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that require fluorinated aromatic components for enhanced activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the development of fluorinated compounds for electronic displays and optical devices.
• Organic Synthesis & Research: A versatile reagent for coupling reactions (e.g., Suzuki, Stille) and for introducing the 3,5-difluoro-4-methoxybenzoyl moiety into more complex molecular architectures.
• Material Science Precursor: Employed in the synthesis of specialized polymers and coatings where fluorinated aromatic units impart desirable properties like chemical resistance and low surface energy.

Basic Information

Product Name	Methyl 3,5-Difluoro-4-Methoxybenzoate
CAS No.	329-45-3
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	Benzoic acid, 3,5-difluoro-4-methoxy-, methyl ester; Methyl 3,5-difluoro-4-methoxybenzoate; 4-Methoxy-3,5-difluorobenzoic acid methyl ester; 3,5-Difluoro-4-methoxybenzoic acid methyl ester; Methyl 4-methoxy-3,5-difluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3,5-Difluoro-4-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.