Description

Methyl 3,5-Dibromo-4-Fluorobenzoate is a high-purity halogenated aromatic ester, serving as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block. Its unique structure, featuring bromine and fluorine substituents, makes it indispensable for constructing complex molecules in medicinal chemistry and material science. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the dibromo-fluorobenzene core is functional.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing halogenated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of bromine substituents.
• Fluorine Chemistry Research: Utilized in academic and industrial R&D to study the effects of fluorine introduction on molecular properties like bioavailability and metabolic stability.
• Polymer Modification: Acts as a monomer or modifier in the synthesis of specialty polymers with enhanced thermal or chemical resistance.

Basic Information

Item	Detail
Product Name	Methyl 3,5-Dibromo-4-Fluorobenzoate
CAS No.	329-43-1
Molecular Formula	C8H5Br2FO2
Molecular Weight	311.93 g/mol
Synonyms	3,5-Dibromo-4-fluorobenzoic acid methyl ester; Methyl 3,5-dibromo-4-fluorobenzoate; Benzoic acid, 3,5-dibromo-4-fluoro-, methyl ester; 4-Fluoro-3,5-dibromobenzoic acid methyl ester; Methyl 4-fluoro-3,5-dibromobenzoate; 329-43-1; Methyl ester of 3,5-dibromo-4-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 3,5-Dibromo-4-Fluorobenzoate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent batch-to-batch reliability. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.