Description

3-(Trifluoromethyl)Benzoyl Fluoride is a versatile and highly reactive organofluorine building block. Its value lies in the trifluoromethyl and acyl fluoride functional groups, which enable efficient synthesis of complex molecules for advanced material and pharmaceutical applications. This compound is essential for R&D and production chemists in the agrochemical, pharmaceutical, and specialty chemical industries seeking to incorporate fluorine atoms for enhanced biological activity and material properties.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing active pharmaceutical ingredients (APIs) containing the trifluoromethyl group, which improves metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group enhances efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a critical building block for fluorine-containing compounds used in electronic display technologies.
• Polymer & Resin Modifier: Imparts unique properties like chemical resistance and low surface energy to specialty polymers and coatings.
• Cross-coupling Reactions: Acts as an electrophile in palladium-catalyzed and other cross-coupling reactions to form carbon-carbon bonds.
• Fluorination Agent: Utilized as a source of fluorine atoms or the benzoyl moiety in selective fluorination and acylation processes.

Basic Information

Product Name	3-(Trifluoromethyl)Benzoyl Fluoride
CAS No.	328-99-4
Molecular Formula	C8H4F4O
Molecular Weight	192.11 g/mol
Synonyms	m-(Trifluoromethyl)benzoyl fluoride; 3-(Trifluoromethyl)benzoyl fluoride; α,α,α-Trifluoro-m-toluoyl fluoride; m-Trifluoromethylbenzoyl fluoride; Benzoyl fluoride, 3-(trifluoromethyl)-; 3-Trifluoromethylbenzoyl fluoride; 328-99-4; m-CF3-C6H4-COF
EINECS	206-334-5

Quality Control

Our 3-(Trifluoromethyl)Benzoyl Fluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.