Description

2-Bromo-4-(Trifluoromethyl)Benzoic Acid is a versatile halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining bromine and trifluoromethyl substituents, enables precise molecular modifications essential for developing high-value compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research for new drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a precursor for more complex carboxylic acid derivatives and metal-organic frameworks.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic pathways and creating novel fluorinated compounds.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Benzoic Acid
CAS No.	328-89-2
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	2-Bromo-α,α,α-trifluoro-p-toluic Acid; Benzoic acid, 2-bromo-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-bromobenzoic Acid; 2-Bromo-4-trifluoromethylbenzoic Acid; α,α,α-Trifluoro-2-bromo-4-methylbenzoic Acid; o-Bromo-α,α,α-trifluoro-p-toluic Acid; 2-Bromo-α,α,α-trifluoro-4-methylbenzoic Acid
EINECS	206-330-5

Quality Control

Our 2-Bromo-4-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.