Description

2-Fluoro-3-Nitrobenzoic Acid is a high-purity, versatile aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Used in the development of fluorinated organic semiconductors and liquid crystal compounds for electronic displays and lighting.
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized nitro- and fluoro-substituted dyes and pigments with specific color fastness and spectral properties.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and reaction pathways.

Basic Information

Product Name	2-Fluoro-3-Nitrobenzoic Acid
CAS No.	317-46-4
Molecular Formula	C7H4FNO4
Molecular Weight	185.11 g/mol
Synonyms	3-Nitro-2-fluorobenzoic Acid; 2-Fluoro-3-nitro-benzoic Acid; Benzoic acid, 2-fluoro-3-nitro-; NSC 404083; 2-Fluoro-3-nitrobenzoic acid; 2-Fluoro-3-nitrobenzenecarboxylic acid; 3-Nitro-2-fluorobenzenecarboxylic acid
EINECS	206-264-3

Quality Control

Our 2-Fluoro-3-Nitrobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	155°C - 160°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.