Description

Benzoic Acid, 4-[(Trifluoromethyl)Sulfonyl]- is a high-value, functionalized benzoic acid derivative characterized by a potent trifluoromethanesulfonyl substituent. This compound is a critical synthetic intermediate and building block, prized for its ability to impart unique electronic and steric properties to target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or trifluoromethyl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethylsulfonyl group contributes to efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands in catalysis and as a component in organometallic complexes.
• Material Science: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis & Research: A versatile reagent for introducing the 4-(trifluoromethylsulfonyl)benzoic acid moiety in medicinal chemistry and process development.

Basic Information

Item	Details
Product Name	Benzoic Acid, 4-[(Trifluoromethyl)Sulfonyl]-
CAS No.	312-22-1
Molecular Formula	C8H5F3O4S
Molecular Weight	254.18 g/mol
Synonyms	4-(Trifluoromethylsulfonyl)benzoic Acid; α,α,α-Trifluoro-4-sulfobenzoic Acid; p-(Trifluoromethylsulfonyl)benzoic Acid; Benzoic acid, p-[(trifluoromethyl)sulfonyl]-; 4-Carboxybenzenesulfonyl Fluoride, Trifluoro Derivative; TFSBA
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-[(Trifluoromethyl)Sulfonyl]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.