Description

[2S-(2Alpha,5Alpha,6Beta)]-6-[[1,1'-Biphenyl]-2-Ylformamido]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic β-lactam structure. This compound is critical for the synthesis and research of novel antibiotics and other biologically active molecules, offering a key building block for medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel β-lactam antibiotics and other specialized active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Biochemical Research: Used in studies investigating enzyme inhibition, particularly those targeting bacterial cell wall synthesis.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a specific, stereochemically defined β-lactam core.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	[2S-(2Alpha,5Alpha,6Beta)]-6-[[1,1'-Biphenyl]-2-Ylformamido]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid
CAS No.	304-43-8
Molecular Formula	C23H22N2O4S
Molecular Weight	422.50 g/mol
Synonyms	6-([1,1'-Biphenyl]-2-ylformamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-([1,1'-Biphenyl]-2-ylcarboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Biphenyl Penicillin Derivative; 6-(Biphenyl-2-carboxamido)penicillanic acid derivative; 304-43-8; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our [2S-(2Alpha,5Alpha,6Beta)]-6-[[1,1'-Biphenyl]-2-Ylformamido]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.