Description

Benzoic Acid, 4-Bromo-5-Chloro-2,3-Difluoro- is a highly functionalized benzoic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its multi-halogenated structure makes it a valuable building block for introducing specific steric and electronic properties into target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors. Its precise substitution pattern enables the synthesis of complex molecules with tailored biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores to modulate bioavailability and receptor binding.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the difluoro and chloro/bromo groups contribute to metabolic stability and target specificity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals, influencing material properties like thermal stability and dielectric constant.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex polycyclic structures for various R&D applications.
• Chemical Biology Probe Development: Utilized as a scaffold for creating fluorescent tags or photoaffinity labels to study biological processes and protein interactions.

Basic Information

Item	Details
Product Name	Benzoic Acid, 4-Bromo-5-Chloro-2,3-Difluoro-
CAS No.	2487481-74-1
Molecular Formula	C7H2BrClF2O2
Molecular Weight	271.45 g/mol
Synonyms	4-Bromo-5-chloro-2,3-difluorobenzoic acid; 2,3-Difluoro-4-bromo-5-chlorobenzoic acid; Benzoic acid, 4-bromo-5-chloro-2,3-difluoro-; 4-Bromo-5-chloro-2,3-difluorobenzoic acid; 2,3-Difluoro-4-bromo-5-chloro-benzoic acid; 2487481-74-1; 4-Br-5-Cl-2,3-F2-BA
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Bromo-5-Chloro-2,3-Difluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.