Description

2-(Difluoromethyl)-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms, which are essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorination enhances efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Employed in the synthesis of electron-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Chemical Research: A versatile reagent for exploring novel fluorination reactions and constructing complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	2-(Difluoromethyl)-5-Fluorobenzoic Acid
CAS No.	2248349-16-6
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	5-Fluoro-2-(difluoromethyl)benzoic Acid; 2-(Difluoromethyl)-5-fluorobenzoic Acid; Benzoic acid, 5-fluoro-2-(difluoromethyl)-; α,α-Difluoro-5-fluoroorthanisic Acid; 5-Fluoro-α,α-difluoro-o-toluic Acid; DFMFBA; 2248349-16-6
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethyl)-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.