Description

Methyl 3-Chloro-2-Fluoro-4-Methoxybenzoate is a high-purity fluorinated benzoate ester, a key synthetic intermediate valued for its role in constructing complex molecular architectures. Its precise chemical structure, featuring strategically placed halogen and methoxy substituents, makes it an essential building block in advanced organic synthesis. This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzene or halogenated benzoate core.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Liquid Crystal & Electronic Chemicals: A potential building block for fluorinated liquid crystal compounds and other electronic materials requiring specific dielectric properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to introduce complex aromatic fragments.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Methyl 3-Chloro-2-Fluoro-4-Methoxybenzoate
CAS No.	2121309-20-2
Molecular Formula	C9H8ClFO3
Molecular Weight	218.61 g/mol
Synonyms	Methyl 3-chloro-2-fluoro-4-methoxybenzoate; 3-Chloro-2-fluoro-4-methoxybenzoic acid methyl ester; Benzoic acid, 3-chloro-2-fluoro-4-methoxy-, methyl ester; Methyl 2-fluoro-3-chloro-4-methoxybenzoate; 2-Fluoro-3-chloro-4-methoxybenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-2-Fluoro-4-Methoxybenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to traceability and documentation supports our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.