Description

3-Bromo-2-Fluoro-5-(Trifluoromethyl)Benzoic Acid is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique halogenated and trifluoromethylated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine and trifluoromethyl groups enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the creation of functionalized monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Item	Detail
Product Name	3-Bromo-2-Fluoro-5-(Trifluoromethyl)Benzoic Acid
CAS No.	2091606-48-1
Molecular Formula	C8H3BrF4O2
Molecular Weight	287.01 g/mol
Synonyms	3-Bromo-2-fluoro-5-(trifluoromethyl)benzoic acid; 2-Fluoro-3-bromo-5-(trifluoromethyl)benzoic acid; Benzoic acid, 3-bromo-2-fluoro-5-(trifluoromethyl)-; 2091606-48-1; 3-Br-2-F-5-CF3-BA
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-2-Fluoro-5-(Trifluoromethyl)Benzoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.