Description

Bis(Trifluoroacetic Acid) is a specialized fluorinated organic acid derivative, known for its potent acidity and utility as a high-performance reagent and building block. This compound is critical for introducing trifluoroacetyl groups and for use as a catalyst or solvent in demanding synthetic processes where strong acidity and fluorination effects are required. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reactive intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing trifluoroacetyl protecting groups or as a catalyst in peptide synthesis.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and stability.
• Polymer & Material Science: Serves as a monomer or modifier in the creation of specialty fluoropolymers with unique chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed as a strong acid catalyst or solvent in various organic transformations, including esterifications, acylations, and condensations.
• Analytical Chemistry: Utilized in sample preparation and derivatization for techniques like HPLC and GC-MS to improve detection of specific analytes.
• Electronics & Semiconductor Manufacturing: Acts as an etching agent or cleaning solvent in the production of electronic components due to its reactivity and purity.

Basic Information

Product Name	Bis(Trifluoroacetic Acid)
CAS No.	2068138-20-3
Molecular Formula	C4HF6O4 (Contact for details)
Molecular Weight	Contact for details
Synonyms	Bis(TFA); Di(trifluoroacetic) acid; Trifluoroacetic acid dimer; Hexafluorodiaectic acid; 1,1,1,3,3,3-Hexafluoro-2,2-propanediol di(trifluoroacetate); Perfluorodiaectic acid; TFA Dimer
EINECS	Contact for details

Quality Control

Our Bis(Trifluoroacetic Acid) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, containers must be kept tightly sealed to prevent moisture absorption and volatilization. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.