Description

4-Bromo-2-Chloro-5-Fluoro-Benzoic Acid Ethyl Ester is a high-purity, multi-halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, functionalized aromatic core for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists in fine chemical, pharmaceutical R&D, and agrochemical manufacturing who require reliable, high-quality intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen pattern influences bioactivity and environmental stability.
• Ligand and Material Science Precursor: Serves as a starting material for creating specialized ligands for catalysis or functional monomers for advanced polymeric materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-Bromo-2-Chloro-5-Fluoro-Benzoic Acid Ethyl Ester
CAS No.	2060616-64-8
Molecular Formula	C9H7BrClFO2
Molecular Weight	281.51 g/mol
Synonyms	Ethyl 4-Bromo-2-chloro-5-fluorobenzoate; Benzoic acid, 4-bromo-2-chloro-5-fluoro-, ethyl ester; 4-Bromo-2-chloro-5-fluorobenzoic acid ethyl ester; 2-Chloro-4-bromo-5-fluorobenzoic acid ethyl ester; 5-Fluoro-4-bromo-2-chlorobenzoic acid ethyl ester; Ethyl 4-bromo-2-chloro-5-fluorobenzoate; 2060616-64-8
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-Chloro-5-Fluoro-Benzoic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in cGMP and ISO 9001 environments for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.