Description

4-Fluoro-3-Nitrobenzoic Acid Benzyl Ester is a high-purity, multifunctional chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorine atom and a nitro group on a benzoic acid benzyl ester backbone, making it a versatile building block for creating complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme inhibitors or receptor modulators where the fluorine and nitro groups are critical for bioactivity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where its structural motifs can contribute to enhanced efficacy and environmental selectivity.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for advanced electronic materials, including liquid crystal displays and organic light-emitting diodes, due to its aromatic and ester functionality.
• Polymer Modification: Employed to introduce fluorinated and nitro-aromatic groups into polymer chains, altering properties like thermal stability, solubility, and optical characteristics.
• Dye & Pigment Chemistry: Acts as an intermediate in the production of specialized dyes and pigments, where the nitro group is often a key chromophore component.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl systems common in many advanced chemicals.

Basic Information

Product Name	4-Fluoro-3-Nitrobenzoic Acid Benzyl Ester
CAS No.	291528-32-0
Molecular Formula	C14H10FNO4
Molecular Weight	275.23 g/mol
Synonyms	Benzyl 4-Fluoro-3-nitrobenzoate; Benzoic acid, 4-fluoro-3-nitro-, phenylmethyl ester; 3-Nitro-4-fluorobenzoic acid benzyl ester; 4-Fluoro-3-nitro-benzoic acid benzyl ester; NSC 405124; Phenylmethyl 4-fluoro-3-nitrobenzoate; (4-Fluoro-3-nitrophenyl)carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Nitrobenzoic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.