Description

2-[3,5-Bis(Trifluoromethyl)Phenyl]Propanoic Acid is a high-value fluorinated aromatic building block characterized by its unique trifluoromethyl-substituted phenyl core. This compound is essential for introducing lipophilicity, metabolic stability, and electron-withdrawing properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Organic Electronics: Employed in the research and production of organic semiconductors and electron-transport materials for OLEDs and photovoltaic cells.
• Advanced Material Research: Utilized in polymer chemistry to create specialty fluoropolymers with enhanced chemical resistance and surface properties.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies, including cross-coupling reactions and asymmetric synthesis.

Basic Information

Product Name	2-[3,5-Bis(Trifluoromethyl)Phenyl]Propanoic Acid
CAS No.	289686-73-3
Molecular Formula	C11H7F6O2
Molecular Weight	270.16 g/mol
Synonyms	2-(3,5-Bis(trifluoromethyl)phenyl)propanoic acid; α-Methyl-3,5-bis(trifluoromethyl)benzenepropanoic acid; 3,5-Bis(trifluoromethyl)hydratropic acid; 2-[3,5-Bis(trifluoromethyl)phenyl]propionic acid; 289686-73-3; Hydratropic acid, 3',5'-bis(trifluoromethyl)-; 2-(3,5-Bis(trifluoromethyl)phenyl)propionic Acid
EINECS	Contact for details

Quality Control

Our production of 2-[3,5-Bis(Trifluoromethyl)Phenyl]Propanoic Acid adheres to stringent quality management protocols. Each batch is analytically verified using advanced techniques including HPLC, GC, and NMR to ensure high purity and consistent lot-to-lot performance. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.