Description

2-Chloro-3,6-Difluorobenzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen substituents, which enable precise structural modifications and introduce unique electronic properties into target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated benzoic acid scaffold.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the halogenated aromatic ring.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where fluorine atoms are crucial for tuning electronic properties and stability.
• Polymer Modification: Incorporated as a monomer or additive to impart specific chemical resistance, thermal stability, or surface properties to specialty polymers.
• Cross-Coupling Reactions: The chlorine atom provides an excellent handle for further functionalization via palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig couplings.
• Organic Synthesis Research: A versatile reagent for academic and industrial R&D focused on exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	2-Chloro-3,6-Difluorobenzoic Acid
CAS No.	287172-74-1
Molecular Formula	C7H3ClF2O2
Molecular Weight	192.55 g/mol
Synonyms	3,6-Difluoro-2-chlorobenzoic Acid; Benzoic acid, 2-chloro-3,6-difluoro-; 2-Chloro-3,6-difluorobenzoic acid; 2-Chloro-3,6-difluoro-benzoic acid; 287172-74-1; 2-Chloro-3,6-difluorobenzoic acid (CAS 287172-74-1)
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,6-Difluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The container must be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.