Description

3-Methoxy-4-(Trifluoromethyl)Benzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its trifluoromethyl and methoxy substituents, which are critical for modulating the lipophilicity, metabolic stability, and electronic properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke fine chemicals.

Basic Information

Product Name	3-Methoxy-4-(Trifluoromethyl)Benzoic Acid
CAS No.	276861-63-3
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	3-Methoxy-4-(trifluoromethyl)benzoic acid; 4-(Trifluoromethyl)-3-methoxybenzoic acid; 3-Methoxy-α,α,α-trifluoro-p-toluic acid; Benzoic acid, 3-methoxy-4-(trifluoromethyl)-; 276861-63-3; 3-Methoxy-4-trifluoromethylbenzoic acid; 4-Carboxy-2-methoxybenzotrifluoride
EINECS	Contact for details

Quality Control

Our production of 3-Methoxy-4-(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.