Description

(R)-(-)-1-(Benzofuran-2-Yl)-2-Propylaminopentane Hydrochloride is a high-purity chiral amine hydrochloride salt, a key building block in advanced organic synthesis. This compound matters for its role as a critical intermediate in the research and development of novel pharmaceutical agents, particularly those targeting the central nervous system. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of potential therapeutic compounds, including serotonin-norepinephrine-dopamine reuptake inhibitors (SNDRIs) and other CNS-active molecules.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor in drug discovery programs for structure-activity relationship (SAR) studies.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in API manufacturing.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Academic Research: Used in universities and research institutes for studies in organic chemistry, pharmacology, and neurochemistry.

Basic Information

Product Name	(R)-(-)-1-(Benzofuran-2-Yl)-2-Propylaminopentane Hydrochloride
CAS No.	265130-22-1
Molecular Formula	C16H24ClNO
Molecular Weight	281.82 g/mol
Synonyms	(R)-1-(Benzofuran-2-yl)-N-propylpentan-2-amine hydrochloride; (R)-(-)-1-(2-Benzofuranyl)-2-(propylamino)pentane hydrochloride; BPAP HCl (R-enantiomer); (R)-BPAP hydrochloride; (R)-(-)-BPAP HCl; (R)-1-(1-Benzofuran-2-yl)-2-propylaminopentane hydrochloride; (R)-(-)-1-(Benzofuranyl-2)-2-propylaminopentane HCl
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-(Benzofuran-2-Yl)-2-Propylaminopentane Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric purity and identity confirmation by spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.