Description

4-Methyl-3-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block characterized by its benzoic acid core substituted with a methyl and a trifluoromethyl group. This compound matters for its role as a versatile intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group is prized for its ability to modulate lipophilicity, metabolic stability, and bioavailability. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the CF3 group contributes to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Incorporated into polymer chains to impart specific chemical resistance, thermal stability, or surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and amide formations for complex molecule assembly in research.
• Coordination Chemistry Ligand: The carboxylic acid functionality allows it to act as a ligand for metal complexes in catalytic systems.

Basic Information

Product Name	4-Methyl-3-(Trifluoromethyl)Benzoic Acid
CAS No.	261952-01-6
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3-Trifluoromethyl-4-methylbenzoic acid; 4-Methyl-3-(trifluoromethyl)benzoic acid; Benzoic acid, 4-methyl-3-(trifluoromethyl)-; 3-Carboxy-6-methylbenzotrifluoride; α,α,α-Trifluoro-4-methyl-m-toluic acid; 4-Methyl-α,α,α-trifluoro-m-toluic acid; 3-(Trifluoromethyl)-p-toluic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.