Description

3,5-Difluoro-4-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block characterized by its benzoic acid core substituted with fluorine and trifluoromethyl groups. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique electronic and steric properties are leveraged. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) to modify dielectric anisotropy and viscosity.
• Polymer Modification: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a directing group or protecting group in complex multi-step syntheses.
• Material Science Research: Employed in the development of organic semiconductors and other electronic materials.

Basic Information

Item	Details
Product Name	3,5-Difluoro-4-(Trifluoromethyl)Benzoic Acid
CAS No.	261945-09-9
Molecular Formula	C8H3F5O2
Molecular Weight	226.10 g/mol
Synonyms	3,5-Difluoro-4-(trifluoromethyl)benzoic acid; 4-(Trifluoromethyl)-3,5-difluorobenzoic acid; Benzoic acid, 3,5-difluoro-4-(trifluoromethyl)-; 3,5-Difluoro-alpha,alpha,α-trifluoro-p-toluic acid; 261945-09-9; 3,5-Difluoro-4-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.