Description

2,5-Difluoro-4-(Trifluoromethyl)Benzoic Acid is a high-value, multi-fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the aromatic ring, makes it an essential intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Electronic Materials: Employed in the development of organic semiconductors and electron-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex, fluorinated aromatic systems in academic and industrial R&D settings.

Basic Information

Item	Details
Product Name	2,5-Difluoro-4-(Trifluoromethyl)Benzoic Acid
CAS No.	261945-05-5
Molecular Formula	C8H3F5O2
Molecular Weight	226.10 g/mol
Synonyms	2,5-Difluoro-α,α,α-trifluoro-p-toluic acid; 4-(Trifluoromethyl)-2,5-difluorobenzoic acid; Benzoic acid, 2,5-difluoro-4-(trifluoromethyl)-; 2,5-Difluoro-4-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-(Trifluoromethyl)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood or with adequate ventilation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.