Description

3-Chloro-2-Fluorocinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogen-substituted aromatic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the chloro-fluoro substitution pattern can enhance biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds, improving electronic properties and stability.
• Cross-Coupling Reactions: The cinnamic acid framework is suitable for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct more complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent probes or molecular tags for imaging and diagnostic applications.
• Polymer Modification: Can be incorporated as a monomer or additive to impart specific characteristics like UV stability or altered solubility to polymeric materials.

Basic Information

Product Name	3-Chloro-2-Fluorocinnamic Acid
CAS No.	261762-62-3
Molecular Formula	C9H6ClFO2
Molecular Weight	200.59 g/mol
Synonyms	(E)-3-(3-Chloro-2-fluorophenyl)acrylic acid; 3-Chloro-2-fluorocinnamic acid; trans-3-(3-Chloro-2-fluorophenyl)-2-propenoic acid; 2-Fluoro-3-chlorocinnamic acid; (2E)-3-(3-Chloro-2-fluorophenyl)prop-2-enoic acid; 3-Chloro-2-fluoro-trans-cinnamic acid; 3-(3-Chloro-2-fluorophenyl)acrylic Acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluorocinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.