Description

4-Chloro-3-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides exceptional versatility for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in the development of anti-inflammatory and anti-cancer agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Polymer Modification: Acts as a monomer or cross-linking agent to introduce fluorine-containing groups into polymers, enhancing chemical resistance and thermal stability.
• Chemical Research & Development: A versatile scaffold in medicinal and synthetic chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorescent Probe & Dye Synthesis: Utilized in the creation of specialized fluorophores and dyes for analytical and diagnostic applications.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethyl)Cinnamic Acid
CAS No.	257872-87-0
Molecular Formula	C10H6ClF3O2
Molecular Weight	250.60 g/mol
Synonyms	(E)-3-[4-Chloro-3-(trifluoromethyl)phenyl]acrylic acid; 4-Chloro-α-(trifluoromethyl)cinnamic acid; 3-(4-Chloro-3-(trifluoromethyl)phenyl)-2-propenoic acid; 2-Propenoic acid, 3-(4-chloro-3-(trifluoromethyl)phenyl)-, (2E)-; (E)-3-(4-Chloro-3-(trifluoromethyl)phenyl)prop-2-enoic acid; 4-Chloro-3-trifluoromethylcinnamic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Trifluoromethyl)Cinnamic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.