Description

2-Hydroxy-3-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and a trifluoromethyl group, makes it a versatile intermediate for creating compounds with enhanced biological activity and material properties. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine into their molecular designs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Complex Ligand Synthesis: Utilized in the preparation of chelating agents and catalysts for asymmetric synthesis and metal-organic frameworks (MOFs).
• Research & Development: A valuable reagent for medicinal chemistry and material science research in academic and industrial R&D laboratories.

Basic Information

Item	Detail
Product Name	2-Hydroxy-3-(Trifluoromethyl)Benzoic Acid
CAS No.	251300-32-0
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	3-(Trifluoromethyl)salicylic acid; 2-Hydroxy-3-trifluoromethylbenzoic acid; Benzoic acid, 2-hydroxy-3-(trifluoromethyl)-; 3-Trifluoromethylsalicylic acid; α-Hydroxy-3-(trifluoromethyl)benzoic acid; 2-Hydroxy-m-trifluoromethylbenzoic acid; Salicylic acid, 3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Hydroxy-3-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent batch-to-batch quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.