Description

2-Fluoro-5-Methanesulfonylbenzoic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a methanesulfonyl group ortho to a fluorine atom, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine and sulfone groups can modulate biological activity and stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Advanced Material Development: A potential monomer or modifier in the synthesis of specialty polymers with tailored electronic or surface properties.

Basic Information

Product Name	2-Fluoro-5-Methanesulfonylbenzoic Acid
CAS No.	247569-56-8
Molecular Formula	C8H7FO4S
Molecular Weight	218.20 g/mol
Synonyms	5-(Methylsulfonyl)-2-fluorobenzoic Acid; 2-Fluoro-5-(methylsulfonyl)benzoic Acid; Benzoic acid, 2-fluoro-5-(methylsulfonyl)-; 2-Fluoro-5-methanesulphonylbenzoic Acid; 2-Fluoro-5-(methanesulfonyl)benzoic Acid; 247569-56-8; 2-Fluoro-5-methylsulfonylbenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methanesulfonylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.