Description

3-(3-Fluorophenyl)-2-Hydroxypropionic Acid is a versatile fluorinated aromatic building block and chiral intermediate of significant interest in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a benzylic hydroxyl group adjacent to a fluorinated phenyl ring, makes it a critical precursor for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides and pesticides with improved efficacy and selectivity.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of specialty fluorinated compounds for electronics, liquid crystals, and advanced materials.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, including studies on fluorination effects and stereoselective transformations.

Basic Information

Product Name	3-(3-Fluorophenyl)-2-Hydroxypropionic Acid
CAS No.	246137-12-2
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	2-Hydroxy-3-(3-fluorophenyl)propanoic Acid; 3-(3-Fluorophenyl)lactic Acid; (R/S)-3-(3-Fluorophenyl)-2-hydroxypropionic Acid; 3-Fluoro-β-hydroxyphenylpropionic Acid; DL-3-(3-Fluorophenyl)lactic Acid; β-Hydroxy-3-fluorohydrocinnamic Acid; 3-(m-Fluorophenyl)-2-hydroxypropionic Acid
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)-2-Hydroxypropionic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.