Description

Methyl 5-Chloro-2-Fluoro-4-Hydroxybenzoate is a high-purity, multi-functional benzoate ester derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise molecular architecture, which incorporates halogen and hydroxyl functional groups, enabling selective chemical transformations. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex active molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated aromatic structure.
• Liquid Crystal Material Precursor: Serves as a starting material for the synthesis of fluorinated liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diode (OLED) Research: Investigated as a core component for developing novel electron-transport or host materials in OLED devices.
• Polymer Modification Agent: Acts as a functional monomer or cross-linking agent to introduce specific properties into specialty polymers.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Methyl 5-Chloro-2-Fluoro-4-Hydroxybenzoate
CAS No.	245743-64-0
Molecular Formula	C8H6ClFO3
Molecular Weight	204.58 g/mol
Synonyms	5-Chloro-2-fluoro-4-hydroxybenzoic acid methyl ester; Methyl 5-chloro-2-fluoro-4-hydroxybenzoate; Benzoic acid, 5-chloro-2-fluoro-4-hydroxy-, methyl ester; 4-Hydroxy-5-chloro-2-fluorobenzoic acid methyl ester; Methyl 4-hydroxy-5-chloro-2-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-2-Fluoro-4-Hydroxybenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide Certificates of Analysis (COA) with each shipment, detailing all specification results to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.