Description

3,4-Difluoro-5-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both difluoro and trifluoromethyl substituents, makes it a critical intermediate for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated compounds used in electronic displays, leveraging its stable aromatic core and fluorine content.
• Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine into high-performance polymers, improving chemical resistance and thermal stability.
• Organic Light-Emitting Diodes (OLEDs): Utilized in the synthesis of electron-transport materials and emissive layer components for display and lighting technologies.
• Chemical Research & Development: A versatile reagent for exploring new reactions and creating complex, fluorinated molecular architectures in academic and industrial labs.

Basic Information

Item	Detail
Product Name	3,4-Difluoro-5-(Trifluoromethyl)Benzoic Acid
CAS No.	237761-76-1
Molecular Formula	C8H3F5O2
Molecular Weight	226.10 g/mol
Synonyms	5-(Trifluoromethyl)-3,4-difluorobenzoic Acid; 3,4-Difluoro-5-trifluoromethylbenzoic Acid; Benzoic acid, 3,4-difluoro-5-(trifluoromethyl)-; 237761-76-1; 3,4-Difluoro-alpha,alpha,α-trifluoro-m-toluic Acid
EINECS	Contact for details

Quality Control

Every batch of 3,4-Difluoro-5-(Trifluoromethyl)Benzoic Acid is manufactured and tested under a strict quality management system. We guarantee high-purity material suitable for demanding synthetic applications, with comprehensive testing including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.