Description

Methyl 3-Chloro-4-Fluorobenzoate is a high-purity fluorinated aromatic ester serving as a critical building block in advanced organic synthesis. This compound matters for its role in introducing both chloro and fluoro substituents onto a benzoate core, enabling precise modulation of electronic and steric properties in target molecules. It is essential for R&D chemists and process engineers in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules with fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the chloro-fluoro substitution pattern is beneficial.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic display and lighting applications.
• Organic Ligand Preparation: Employed in the synthesis of specialized ligands for catalysis and material science research.
• Polymer Modification: Acts as a monomer or modifier to introduce specific functional groups into polymer chains, enhancing material properties.
• General Organic Synthesis: A versatile reagent for coupling reactions, esterifications, and further functional group transformations in complex molecule assembly.

Basic Information

Product Name	Methyl 3-Chloro-4-Fluorobenzoate
CAS No.	234082-35-0
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	3-Chloro-4-fluorobenzoic acid methyl ester; Methyl 3-chloro-4-fluorobenzoate; Benzoic acid, 3-chloro-4-fluoro-, methyl ester; 4-Fluoro-3-chlorobenzoic acid methyl ester; Methyl 4-fluoro-3-chlorobenzoate; 3-Chloro-4-fluorobenzoic acid, methyl ester; Methyl ester of 3-chloro-4-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.