Description

Ralfinamide is a high-purity, non-opioid analgesic agent with a novel mechanism of action. This compound is of significant interest in pharmaceutical research and development, particularly for its potential in managing neuropathic and chronic pain conditions. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the synthesis of new chemical entities (NCEs) and advanced therapeutic research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel analgesic drug candidates.
• Neurological Research: Used in preclinical and clinical studies targeting sodium channel modulation for pain management.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Active Pharmaceutical Ingredient (API) Development: Integral to formulation studies for developing finished dosage forms.
• Biochemical Research: Utilized in vitro assays to study interactions with neuronal targets and pathways.

Basic Information

Product Name	Ralfinamide
CAS No.	229309-19-7
Molecular Formula	C17H16F3N3O
Molecular Weight	335.33 g/mol
Synonyms	(2R)-N-(4-Fluorobenzyl)-2-methyl-4,5,6,7-tetrahydro-1-benzothieno[2,3-c]pyridine-3-carboxamide; NW-1029; FCE-26742; Ralfinamide Hydrochloride (salt form); (R)-N-[(4-Fluorophenyl)methyl]-2-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our Ralfinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR to ensure it meets stringent pharmaceutical-grade standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.