Description

2,6-Difluoro-3-Iodobenzoic Acid is a high-value, multi-functional halogenated benzoic acid derivative. This compound serves as a critical synthetic intermediate, prized for its unique reactivity imparted by the strategic positioning of fluorine and iodine atoms on the aromatic ring. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for advanced organic materials, including liquid crystals and specialty polymers requiring halogenated aromatic components.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine atom, enabling efficient carbon-carbon bond formation.
• Chemical Derivatization: The carboxylic acid group allows for further functionalization to amides, esters, and other derivatives, expanding its utility in custom synthesis.

Basic Information

Product Name	2,6-Difluoro-3-Iodobenzoic Acid
CAS No.	229178-74-9
Molecular Formula	C7H3F2IO2
Molecular Weight	283.99 g/mol
Synonyms	3-Iodo-2,6-difluorobenzoic Acid; Benzoic acid, 2,6-difluoro-3-iodo-; 2,6-Difluoro-3-iodobenzoic acid; 229178-74-9; 3-Carboxy-2,6-difluoroiodobenzene
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Iodobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.