Description

Benzamide,4-Fluoro-n-[2-[4-(2-Methoxyphenyl)-1-Piperazinyl]Ethyl]-n-2-Pyridinyl-,Dihydrochloride is a high-purity, complex organic compound with significant pharmacological research interest. This compound is valued for its role as a key intermediate or reference standard in the development of novel therapeutic agents targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and neuroscience studies.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or building block in the synthesis of potential drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Studies: Used as a reference standard or lead compound for structure-activity relationship (SAR) optimization and target validation.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening assays for specific receptor targets.
• Academic Research: Utilized in university and institutional labs for fundamental research in neuropharmacology and organic synthesis methodologies.
• Contract Manufacturing (CMO): Supplied to specialized CMOs for the cGMP-compliant production of non-clinical and clinical trial materials.
• Analytical Reference Standard: Provides a high-purity standard for method development and quality control in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	Benzamide,4-Fluoro-n-[2-[4-(2-Methoxyphenyl)-1-Piperazinyl]Ethyl]-n-2-Pyridinyl-,Dihydrochloride
CAS No.	223699-41-0
Molecular Formula	C25H28FN5O2 • 2HCl
Molecular Weight	522.44 g/mol (Free base: 449.52 g/mol)
Synonyms	4-Fluoro-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-(pyridin-2-yl)benzamide dihydrochloride; N-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)-4-fluorobenzamide dihydrochloride; 4-Fluoro-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-2-pyridinylbenzamide dihydrochloride; CAS 223699-41-0; 1-[2-[N-(4-Fluorobenzoyl)-N-(2-pyridyl)amino]ethyl]-4-(2-methoxyphenyl)piperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our Benzamide,4-Fluoro-n-[2-[4-(2-Methoxyphenyl)-1-Piperazinyl]Ethyl]-n-2-Pyridinyl-,Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identification, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.