Description

Tolterodine CAS NO 215929-30-9 is a potent and selective muscarinic receptor antagonist, serving as a key active pharmaceutical ingredient (API). Its primary value lies in its therapeutic efficacy for managing overactive bladder (OAB) syndrome, significantly improving patient quality of life. This high-purity compound is essential for pharmaceutical manufacturers engaged in the development and production of finished dosage forms, such as tablets and capsules, for the global urology market.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of overactive bladder (OAB) with symptoms of urinary urgency, frequency, and incontinence.
• Extended-Release Formulations: Utilized in controlled-release tablet technologies to provide steady, 24-hour therapeutic effect from a single daily dose.
• Immediate-Release Formulations: Incorporated into standard tablets for flexible dosing regimens as prescribed.
• Generic Drug Manufacturing: A critical component for companies producing bioequivalent generic versions of branded tolterodine medications.
• Clinical Research: Serves as a reference standard and raw material in preclinical and clinical studies for new urological treatments.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of finished drug products for various markets.

Basic Information

Item	Detail
Product Name	Tolterodine
CAS No.	215929-30-9
Molecular Formula	C22H31NO
Molecular Weight	325.49 g/mol
Synonyms	(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-methylphenol; (R)-N,N-Diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine; Tolterodine Base; Detrol (brand name); PNU-200583; (R)-Tolterodine
EINECS	Contact for details

Quality Control

Our Tolterodine is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure it conforms to specifications. A Certificate of Analysis (COA) documenting purity, typically ≥98.5% by HPLC, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: ≤0.5% Total impurities: ≤1.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.