Description

Benzoyl Chloride, 2-Fluoro-6-Hydroxy- (9Ci) is a specialized fluorinated benzoyl chloride derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual reactive sites, enabling the selective introduction of the benzoyl moiety and the 2-fluoro-6-hydroxy substitution pattern into target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the development of fluorinated drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic chemicals for display and lighting technologies.
• Polymer Modification: Employed to introduce photoactive or stabilizing benzoyl groups into specialty polymer chains.
• Complex Ligand Synthesis: Used in academic and industrial research to create novel fluorinated ligands for catalysis and material science.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Benzoyl Chloride, 2-Fluoro-6-Hydroxy- (9Ci)
CAS No.	214752-63-3
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	2-Fluoro-6-hydroxybenzoyl chloride; 6-Fluoro-2-hydroxybenzoyl chloride; (2-Fluoro-6-hydroxyphenyl)(chloro)methanone; 2-Fluoro-6-hydroxybenzoic acid chloride; Benzoyl chloride, 2-fluoro-6-hydroxy-
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride, 2-Fluoro-6-Hydroxy- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.