Description

1-(3-Fluorophenyl)Cyclohexanecarboxylic Acid is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound is valued for its unique structural features, which enable the introduction of both a cyclohexyl and a fluorinated aromatic moiety into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for use in medicinal chemistry and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing lipophilic and fluorinated pharmacophores.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorophenyl group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with tailored properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations to construct complex molecular architectures.
• Chemical Reference Standard: Used for analytical method development, calibration, and quality control in laboratories requiring high-purity fluorinated compounds.

Basic Information

Product Name	1-(3-Fluorophenyl)Cyclohexanecarboxylic Acid
CAS No.	214262-98-3
Molecular Formula	C13H15FO2
Molecular Weight	222.26 g/mol
Synonyms	3-Fluoro-α-phenylcyclohexaneacetic acid; Cyclohexanecarboxylic acid, 1-(3-fluorophenyl)-; 1-(3-Fluorophenyl)cyclohexanecarboxylic acid; 3-Fluorophenylcyclohexylacetic acid; α-(3-Fluorophenyl)cyclohexaneacetic acid; (3-Fluorophenyl)cyclohexylmethanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure it meets the specified 98% minimum purity and consistent impurity profile. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in GMP and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.