Description

2-(3,5-Difluorophenyl)-2-Oxoacetic Acid is a high-purity fluorinated aromatic keto acid building block, essential for advanced organic synthesis. Its unique difluorophenyl-oxoacetic acid structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting enzymes and receptors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the difluorophenyl moiety can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of advanced organic materials, including monomers for specialty polymers and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and diagnostics.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(3,5-Difluorophenyl)-2-Oxoacetic Acid
CAS No.	208259-76-1
Molecular Formula	C8H4F2O3
Molecular Weight	186.11 g/mol
Synonyms	2-Oxo-2-(3,5-difluorophenyl)acetic Acid; (3,5-Difluorophenyl)oxoacetic Acid; 3,5-Difluorobenzoylformic Acid; α-Oxo-3,5-difluorobenzeneacetic Acid; 2-(3,5-Difluorophenyl)-2-oxoethanoic Acid; 3,5-Difluorophenylglyoxylic Acid; 208259-76-1; Difluorophenyl Oxoacetic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-(3,5-Difluorophenyl)-2-Oxoacetic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) including HPLC purity, identity confirmation (IR, NMR), and impurity profile is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.