Description

2,3,5,6-Tetrafluoro-4-Hydroxybenzoic Acid Hydrate, 96% is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and specialty materials, where its unique fluorine substitution pattern imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine groups into polymer chains, improving chemical resistance, thermal stability, and surface properties.
• Complex Ligand Synthesis: Useful in preparing fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Research & Development: A valuable reagent for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-4-Hydroxybenzoic Acid Hydrate, 96%
CAS No.	207738-02-1
Molecular Formula	C7H2F4O3 · xH2O
Molecular Weight	214.08 (Anhydrous basis)
Synonyms	2,3,5,6-Tetrafluoro-4-hydroxybenzoic acid hydrate; 4-Hydroxy-2,3,5,6-tetrafluorobenzoic acid hydrate; Benzoic acid, 2,3,5,6-tetrafluoro-4-hydroxy-, hydrate; Tetrafluorohydroxybenzoic acid hydrate; Perfluorohydroxybenzoic acid hydrate; TFHBA hydrate; 207738-02-1 (CAS)
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluoro-4-Hydroxybenzoic Acid Hydrate, 96% undergoes rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Every batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Water Content (KF)	≤ 4.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.