Description

trans-2-Chloro-6-Fluorocinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical pharmaceutical intermediate and versatile organic building block. Its unique halogenated structure makes it invaluable for synthesizing complex molecules in medicinal chemistry and advanced material science. This compound is primarily sought by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and liquid crystal industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for anti-inflammatory and anticancer drug candidates.
• Agrochemical Synthesis: Building block for developing advanced herbicides and pesticides with enhanced efficacy and selectivity.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronic Materials: Serves as a monomer or dopant in the research of organic semiconductors and light-emitting materials.
• Chemical Research & Development: A versatile scaffold for Suzuki-Miyaura and other cross-coupling reactions in academic and industrial R&D.
• Fluorescent Probe Synthesis: Utilized in the design of fluorophore tags and sensors for biochemical assays.

Basic Information

Product Name	trans-2-Chloro-6-Fluorocinnamic Acid
CAS No.	206986-82-5
Molecular Formula	C9H6ClFO2
Molecular Weight	200.59 g/mol
Synonyms	(2E)-3-(2-Chloro-6-fluorophenyl)acrylic Acid; (E)-3-(2-Chloro-6-fluorophenyl)-2-propenoic Acid; 2-Chloro-6-fluorocinnamic Acid (trans); trans-3-(2-Chloro-6-fluorophenyl)acrylic Acid; (E)-2-Chloro-6-fluorocinnamic Acid; 206986-82-5; 2-Chloro-6-fluoro-trans-cinnamic Acid
EINECS	Contact for details

Quality Control

Our trans-2-Chloro-6-Fluorocinnamic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.